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An estimated 40% of people between 80 and 85 have either dementia, which makes independent living difficult, or what's known as mild cognitive impairment.īut diagnosing those conditions requires more than an hour of testing and a thorough history of someone's life, Tan says, not just watching a few seconds of a press conference. "Trying to remember that name of the restaurant that they were in last week or the name of the person that they met for coffee, that is not in itself a sign of dementia," Tan says, "but it's a sign of cognitive aging." A glitch or a problem?Īlzheimer's and other forms of dementia become more common with each passing decade. But in many older people, the brain's ability to quickly retrieve that information becomes less reliable. "As we age, that might diminish to something like six digits, but not zero."Ī healthy brain typically retains its ability to learn and store information. But it's less likely to make a difference to someone who is doing "an executive-level job, where there is a lot of support and a lot more time to do planning and decision making."Īnother cognitive change associated with age involves working memory, which allows us to keep in mind a password or phone number for a few seconds or minutes.Ī typical person in their 20s might be able to reliably hold seven digits in working memory, Sha says. That may be a problem for a race car driver or an airline pilot, Tan says. Slower processing means a person may take longer to respond to a question or make a decision. One reason for the decline is a decrease in the speed at which the brain processes information. "Even the so-called successful agers, if you measure their cognitive performance, you will see certain changes compared to their baseline," Tan says. But all brains lose a step or two with age. Sharon Sha, a clinical professor of neurology at Stanford University.Ĭognitive changes are often associated with diseases like Alzheimer's and other forms of dementia. The temporary inability to remember names, in particular, "is very common as we get older," says Dr. doi: 10.36660/, memory lapses become more common with age, even in people whose brains are perfectly healthy. Frailty among non-elderly patients undergoing cardiac surgery. 2013 8(2):76–88.īottura C, Arcêncio L, Chagas HMA, Evora PRB, Rodrigues AJ. Coronary arteries bypass grafting surgery in elderly patients. Sabzi F, Kazerani H, Jalali A, Samadi M, Ghasemi F. Association of postoperative complications and outcomes following coronary artery bypass grafting. Jawitz OK, Gulack BC, Brennan JM, Thibault DP, Wang A, O’Brien SM, Schroder JN, Gaca JG, Smith PK. Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013. doi: 10.21037/jtd.2018.02.43.īrieger DB, Ng AC, Chow V, D’Souza M, Hyun K, Bannon PG, Kritharides L. Fifty years of coronary artery bypass grafting. Melly L, Torregrossa G, Lee T, Jansens JL, Puskas JD. 5.00, p = 0.051) was shown in the frail patient.įrailty showed a significant association with a worse preoperative independence level, cognitive function, and depression status, as well as increased postoperative complications.Ĭognitive function Coronary artery bypass grafting Depression status Frailty Independence level. A mildly significantly more extended ICU stay (6.00 vs. 19.0%), as well as a higher Euroscore (1.5 vs. A significantly higher rate of readmission (1.8% vs. 6.00, P < 0.001) was significantly lower in frail cases. According to 3-month follow-up data, postoperative MOCA and GDS scores were comparable between the two groups, while Lawton IADL (8.00 vs.
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Frail patients demonstrated significantly worse baseline MOCA scores (21.08 vs. Of these, 58 cases were classified as frail, and 112 individuals were non-frail, preoperatively. We included 170 patients with a median age of 66 ± 4 years (75.3% male). Outcomes between frail and non-frail groups were compared utilizing T-tests and Mann-Whitney U tests, as appropriate. The incidence of adverse outcomes was investigated at the three-month follow-up. Baseline and three-month follow-up data on frailty using the Frail scale and clinical Frail scale, functional status using the Lawton Instrumental Activities of Daily Living Scale (IADL), cognitive function by Montreal Cognitive Assessment (MoCA), and depression by the Geriatric Depression Scale (GDS) were obtained. This prospective study included patients aged over 60 years undergoing elective CABG at Tehran Heart Center from 2020 to 2022. We assessed the association between frailty and cognitive and clinical complications following CABG.
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Frailty is proposed as a predictor of outcomes in patients undergoing major surgeries, although data on the association of frailty and coronary artery bypass grafting (CABG) are lacking.